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Question 8
All of the following pathways occur as DKA develops EXCEPT
A–Hyperglycemia → glycosuria → dehydration and loss of electrolytes
B–Hyperglycemia → cell dehydration → altered level of consciousness
C–Insulin and glucagon deficiency → increased hepatic gluconeogenesis
D–Lipolysis → ketosis → acidosis
E–Muscle breakdown → azotemia → loss of sodium
Answer & Comments
•C
Comments:
–DKA occurs when inadequate insulin is secreted from pancreatic cells.
–In response, glucagon levels soar.
–The elevated glucagon levels result in gluconeogenesis and glycogenolysis.
–This hyperglycemic state produces an osmotic diuresis, leading to cell dehydration, electrolyte abnormalities, and an altered level of consciousness.
–The catabolic processes of lipolysis and muscle breakdown are also activated.
All of the following pathways occur as DKA develops EXCEPT
A–Hyperglycemia → glycosuria → dehydration and loss of electrolytes
B–Hyperglycemia → cell dehydration → altered level of consciousness
C–Insulin and glucagon deficiency → increased hepatic gluconeogenesis
D–Lipolysis → ketosis → acidosis
E–Muscle breakdown → azotemia → loss of sodium
Answer & Comments
•C
Comments:
–DKA occurs when inadequate insulin is secreted from pancreatic cells.
–In response, glucagon levels soar.
–The elevated glucagon levels result in gluconeogenesis and glycogenolysis.
–This hyperglycemic state produces an osmotic diuresis, leading to cell dehydration, electrolyte abnormalities, and an altered level of consciousness.
–The catabolic processes of lipolysis and muscle breakdown are also activated.
in diabetes, there is dysregulation of islet cell function,
i.e. decresed or absent insulin secretion and increaded glucagon secretion, so (c) is the except answer.
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